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Exhausted and irritable but otherwise healthy? It could be your adrenal glands. "They pump out cortisol and adrenaline hormones which create our 'fight or flight' response to stress," says Charlotte Watts, author of The De-Stress Effect. When unbalanced, cortisol levels can cause low blood pressure, insomnia, poor stamina, anxiety and depression - all symptoms of adrenal fatigue, which experts are calling the stress condition of our generation.